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Computationally identified novel agonists for GPRC6A

New insights into G protein coupled receptor regulation of glucose metabolism by β-cells, skeletal muscle and liver hepatocytes identify GPRC6A as a potential therapeutic target for treating type 2 diabetes mellitus (T2D). Activating GPRC6A with a small molecule drug represents a potential paradigm-...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Pi, Min, Kapoor, Karan, Ye, Ruisong, Hwang, Dong-Jin, Miller, Duane D., Smith, Jeremy C., Baudry, Jerome, Quarles, L. Darryl
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912754/
https://ncbi.nlm.nih.gov/pubmed/29684031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195980
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