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GATA6 phosphorylation by Erk1/2 propels exit from pluripotency and commitment to primitive endoderm
The transcription factor GATA6 and the Fgf/Ras/MAPK signaling pathway are essential for the development of the primitive endoderm (PrE), one of the two lineages derived from the pluripotent inner cell mass (ICM) of mammalian blastocysts. A mutant mouse line in which Gata6-coding exons are replaced w...
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| 出版年: | Dev Biol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912698/ https://ncbi.nlm.nih.gov/pubmed/29454706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2018.02.007 |
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