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The Primitive Endoderm Segregates from the Epiblast in β1 Integrin-Deficient Early Mouse Embryos

We analyzed the mechanism of developmental failure in implanted β1 integrin-null blastocysts and found that primitive endoderm cells are present but segregate away from, instead of forming an epithelial layer covering, the inner cell mass. This cell segregation phenotype was also reproduced in β1 in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Moore, Robert, Tao, Wensi, Smith, Elizabeth R., Xu, Xiang-Xi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911515/
https://ncbi.nlm.nih.gov/pubmed/24277939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00937-13
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