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The Primitive Endoderm Segregates from the Epiblast in β1 Integrin-Deficient Early Mouse Embryos

We analyzed the mechanism of developmental failure in implanted β1 integrin-null blastocysts and found that primitive endoderm cells are present but segregate away from, instead of forming an epithelial layer covering, the inner cell mass. This cell segregation phenotype was also reproduced in β1 in...

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Detalhes bibliográficos
Main Authors: Moore, Robert, Tao, Wensi, Smith, Elizabeth R., Xu, Xiang-Xi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911515/
https://ncbi.nlm.nih.gov/pubmed/24277939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00937-13
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