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The Primitive Endoderm Segregates from the Epiblast in β1 Integrin-Deficient Early Mouse Embryos
We analyzed the mechanism of developmental failure in implanted β1 integrin-null blastocysts and found that primitive endoderm cells are present but segregate away from, instead of forming an epithelial layer covering, the inner cell mass. This cell segregation phenotype was also reproduced in β1 in...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3911515/ https://ncbi.nlm.nih.gov/pubmed/24277939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00937-13 |
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