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Ectopic expression of GATA6 bypasses requirement for Grb2 in primitive endoderm formation
Gene knockouts in mice have showed that Grb2 and GATA6 are essential for the formation of primitive endoderm in blastocysts. Here, we confirmed that implanted Grb2-null blastocysts lack primitive or extraembryonic endoderm cells either at E4.5 or E5.5 stages. We analyzed the relationship between Grb...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299199/ https://ncbi.nlm.nih.gov/pubmed/20925113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22447 |
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