CD103(+)CD11b(+) mucosal classical dendritic cells initiate long-term switched antibody responses to flagellin

Antibody (Ab) responses induced at mucosal and non-mucosal sites demonstrate a significant level of autonomy. Here we demonstrate a key role for mucosal IRF4-dependent CD103(+)CD11b(+) (DP), classical dendritic cells (cDC) in the induction of T-dependent IgG and IgA responses in the mesenteric lymph...

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Udgivet i:Mucosal Immunol
Main Authors: Flores-Langarica, A, Müller Luda, K, Persson, E K, Cook, C N, Bobat, S, Marshall, J L, Dahlgren, M W, Hägerbrand, K, Toellner, K M, Goodall, M D, Withers, D R, Henderson, I R, Johansson Lindbom, B, Cunningham, A F, Agace, W W
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912514/
https://ncbi.nlm.nih.gov/pubmed/29346347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2017.105
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