Bile retinoids imprint intestinal CD103(+) dendritic cells with the ability to generate gut-tropic T cells

Small intestinal lamina propria (SI-LP) CD103(+) dendritic cells (DCs) are imprinted with an ability to metabolize vitamin A (retinol), a property underlying their enhanced capacity to induce the gut-homing receptors CC chemokine receptor-9 and α4β7 on responding T cells. In this study, we demonstra...

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Main Authors: Jaensson-Gyllenbäck, E, Kotarsky, K, Zapata, F, Persson, E K, Gundersen, T E, Blomhoff, R, Agace, W W
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130189/
https://ncbi.nlm.nih.gov/pubmed/21289617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2010.91
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