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Direct observation of the influence of cardiolipin and antibiotics on lipid II binding to MurJ

Translocation of lipid II across cytoplasmic membrane is essential in peptidoglycan biogenesis. Although most steps are understood, identifying the lipid II flippase has yielded conflicting results, and the lipid II binding properties of two candidate flippases, MurJ and FtsW, remain largely unknown...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Bolla, Jani Reddy, Sauer, Joshua B., Wu, Di, Mehmood, Shahid, Allison, Timothy M., Robinson, Carol V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912511/
https://ncbi.nlm.nih.gov/pubmed/29461535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2919
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