The pseudophosphatase phogrin enables glucose-stimulated insulin signaling in pancreatic β cells

Autocrine insulin signaling is critical for pancreatic β-cell growth and activity and is at least partially controlled by protein-tyrosine phosphatases (PTPs) that act on insulin receptors (IRs). The receptor-type PTP phogrin primarily localizes on insulin secretory granules in pancreatic β cells. W...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Torii, Seiji, Kubota, Chisato, Saito, Naoya, Kawano, Ayumi, Hou, Ni, Kobayashi, Masaki, Torii, Ryoko, Hosaka, Masahiro, Kitamura, Tadahiro, Takeuchi, Toshiyuki, Gomi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912479/
https://ncbi.nlm.nih.gov/pubmed/29483197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000301
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