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Hairy and enhancer of split 1 (HES1) protects cells from endoplasmic reticulum stress–induced apoptosis through repression of GADD34

Disruption in endoplasmic reticulum (ER) function, termed ER stress, occurs in many diseases, including neurodegenerative disorders, diabetes, and cancer. Cells respond to ER stress with the unfolded protein response (UPR), which triggers a broad transcriptional program to restore and enhance ER fun...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Lee, Ji Eun, Morrison, William, Hollien, Julie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912459/
https://ncbi.nlm.nih.gov/pubmed/29491143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002124
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