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Association with Endoplasmic Reticulum Promotes Proteasomal Degradation of GADD34 Protein
Stress-induced endogenous and ectopically expressed GADD34 proteins were present both in the cytoplasm and in membranes, with their membrane association showing similar biochemical properties. Deletion of N-terminal sequences in GADD34-GFP proteins highlighted an amphipathic helix, whose hydrophobic...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122225/ https://ncbi.nlm.nih.gov/pubmed/21518769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.212787 |
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