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Association with Endoplasmic Reticulum Promotes Proteasomal Degradation of GADD34 Protein

Stress-induced endogenous and ectopically expressed GADD34 proteins were present both in the cytoplasm and in membranes, with their membrane association showing similar biochemical properties. Deletion of N-terminal sequences in GADD34-GFP proteins highlighted an amphipathic helix, whose hydrophobic...

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Detalhes bibliográficos
Main Authors: Zhou, Wei, Brush, Matthew H., Choy, Meng S., Shenolikar, Shirish
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122225/
https://ncbi.nlm.nih.gov/pubmed/21518769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.212787
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