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TAR DNA-binding protein 43 (TDP-43) liquid–liquid phase separation is mediated by just a few aromatic residues
Eukaryotic cells contain distinct organelles, but not all of these compartments are enclosed by membranes. Some intrinsically disordered proteins mediate membraneless organelle formation through liquid–liquid phase separation (LLPS). LLPS facilitates many biological functions such as regulating RNA...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912450/ https://ncbi.nlm.nih.gov/pubmed/29511089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC117.001037 |
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