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Primordial Germ Cell Transplantation for CRISPR/Cas9-based Leapfrogging in Xenopus
The creation of mutant lines by genome editing is accelerating genetic analysis in many organisms. CRISPR/Cas9 methods have been adapted for use in the African clawed frog, Xenopus, a longstanding model organism for biomedical research. Traditional breeding schemes for creating homozygous mutant lin...
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| Опубликовано в: : | J Vis Exp |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MyJove Corporation
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912334/ https://ncbi.nlm.nih.gov/pubmed/29443056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56035 |
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