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COMMON POLYMORPHISMS OF CHEMOKINE (C-X3-C MOTIF) RECEPTOR 1 GENE MODIFY AMYOTROPHIC LATERAL SCLEROSIS OUTCOME: A POPULATION-BASED STUDY
INTRODUCTION: In the brain, the chemokine (C-X3-C motif) receptor 1 (1CX3CR1) gene is expressed only by microglia, where it acts as a key mediator of the neuron–microglia interactions. We assessed whether the 2 common polymorphisms of the CX3CR1 gene (V249I and T280M) modify amyotrophic lateral scle...
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| Publicado no: | Muscle Nerve |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912184/ https://ncbi.nlm.nih.gov/pubmed/28342179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.25653 |
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