COMMON POLYMORPHISMS OF CHEMOKINE (C-X3-C MOTIF) RECEPTOR 1 GENE MODIFY AMYOTROPHIC LATERAL SCLEROSIS OUTCOME: A POPULATION-BASED STUDY

INTRODUCTION: In the brain, the chemokine (C-X3-C motif) receptor 1 (1CX3CR1) gene is expressed only by microglia, where it acts as a key mediator of the neuron–microglia interactions. We assessed whether the 2 common polymorphisms of the CX3CR1 gene (V249I and T280M) modify amyotrophic lateral scle...

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Bibliografske podrobnosti
izdano v:Muscle Nerve
Main Authors: Calvo, Andrea, Moglia, Cristina, Canosa, Antonio, Cammarosano, Stefania, Ilardi, Antonio, Bertuzzo, Davide, Traynor, Bryan J., Brunetti, Maura, Barberis, Marco, Mora, Gabriele, Casale, Federico, Chiò, Adriano
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912184/
https://ncbi.nlm.nih.gov/pubmed/28342179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.25653
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