Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen

Lipoarabinomannan (LAM), the major antigenic glycolipid of Mycobacterium tuberculosis, is an important immunodiagnostic target for detecting tuberculosis (TB) infection in HIV-1–coinfected patients, and is believed to mediate a number of functions that promote infection and disease development. To p...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Choudhary, Alok, Patel, Deendayal, Honnen, William, Lai, Zhong, Prattipati, Raja Sekhar, Zheng, Ruixiang Blake, Hsueh, Ying-Chao, Gennaro, Maria Laura, Lardizabal, Alfred, Restrepo, Blanca I., Garcia-Viveros, Moncerrato, Joe, Maju, Bai, Yu, Shen, Ke, Sahloul, Kamar, Spencer, John S., Chatterjee, Delphi, Broger, Tobias, Lowary, Todd L., Pinter, Abraham
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2018
Assuntos:
Antigen Recognition and Responses
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911930/
https://ncbi.nlm.nih.gov/pubmed/29610143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701673
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