Analysis of Antibody Responses to Mycobacterium leprae Phenolic Glycolipid I, Lipoarabinomannan, and Recombinant Proteins To Define Disease Subtype-Specific Antigenic Profiles in Leprosy

A simple serodiagnostic test based on the Mycobacterium leprae-specific phenolic glycolipid I(PGL-I), for individuals with leprosy is nearly universally positive in leprosy patients with high bacillary loads but cannot be used as a stand-alone diagnostic test for the entire spectrum of the disease p...

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Hauptverfasser: Spencer, John S., Kim, Hee Jin, Wheat, William H., Chatterjee, Delphi, Balagon, Marivic V., Cellona, Roland V., Tan, Esterlina V., Gelber, Robert, Saunderson, Paul, Duthie, Malcolm S., Reece, Stephen T., Burman, William, Belknap, Robert, Mac Kenzie, William R., Geluk, Annemieke, Oskam, Linda, Dockrell, Hazel M., Brennan, Patrick J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Clinical Laboratory Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067349/
https://ncbi.nlm.nih.gov/pubmed/21177913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00472-10
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