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The MLH1 ATPase Domain is needed for Suppressing Aberrant Formation of Interstitial Telomeric Sequences

Genome instability gives rise to cancer. MLH1, commonly known for its important role in mismatch repair (MMR), DNA damage signaling and double-strand break (DSB) repair, safeguards genome stability. Recently we have reported a novel role of MLH1 in preventing aberrant formation of interstitial telom...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Jia, Pingping, Chai, Weihang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911416/
https://ncbi.nlm.nih.gov/pubmed/29544212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.03.002
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