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The MLH1 ATPase Domain is needed for Suppressing Aberrant Formation of Interstitial Telomeric Sequences

Genome instability gives rise to cancer. MLH1, commonly known for its important role in mismatch repair (MMR), DNA damage signaling and double-strand break (DSB) repair, safeguards genome stability. Recently we have reported a novel role of MLH1 in preventing aberrant formation of interstitial telom...

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Détails bibliographiques
Publié dans:DNA Repair (Amst)
Auteurs principaux: Jia, Pingping, Chai, Weihang
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911416/
https://ncbi.nlm.nih.gov/pubmed/29544212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.03.002
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