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Increased autophagy blocks HER2-mediated breast tumorigenesis
Allelic loss of the autophagy gene, beclin 1/BECN1, increases the risk of patients developing aggressive, including human epidermal growth factor receptor 2 (HER2)-positive, breast cancers; however, it is not known whether autophagy induction may be beneficial in preventing HER2-positive breast tumo...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5910832/ https://ncbi.nlm.nih.gov/pubmed/29610308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717800115 |
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