Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis

Autophagy is an evolutionarily conserved lysosomal degradation pathway that plays an essential role in enabling eukaryotic organisms to adapt to nutrient deprivation and other forms of environmental stress. In metazoan organisms, autophagy is essential for differentiation and normal development; how...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Lee, Eunmyong, Wei, Yongjie, Zou, Zhongju, Tucker, Kathryn, Rakheja, Dinesh, Levine, Beth, Amatruda, James F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper: Autophagy and Cell Death
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356529/
https://ncbi.nlm.nih.gov/pubmed/27655644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12084
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