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MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression
Precise mitotic spindle orientation is essential for both cell fate and tissue organization while defects in this process are associated with tumorigenesis and other diseases. In most animal cell types, the dynein motor complex is anchored at the cell cortex and exerts pulling forces on astral micro...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5910412/ https://ncbi.nlm.nih.gov/pubmed/29679050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24682-8 |
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