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MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression

Precise mitotic spindle orientation is essential for both cell fate and tissue organization while defects in this process are associated with tumorigenesis and other diseases. In most animal cell types, the dynein motor complex is anchored at the cell cortex and exerts pulling forces on astral micro...

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Publicat a:Sci Rep
Autors principals: Vodicska, Barbara, Cerikan, Berati, Schiebel, Elmar, Hoffmann, Ingrid
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910412/
https://ncbi.nlm.nih.gov/pubmed/29679050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24682-8
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