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MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression

Precise mitotic spindle orientation is essential for both cell fate and tissue organization while defects in this process are associated with tumorigenesis and other diseases. In most animal cell types, the dynein motor complex is anchored at the cell cortex and exerts pulling forces on astral micro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vodicska, Barbara, Cerikan, Berati, Schiebel, Elmar, Hoffmann, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910412/
https://ncbi.nlm.nih.gov/pubmed/29679050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24682-8
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