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MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression

Precise mitotic spindle orientation is essential for both cell fate and tissue organization while defects in this process are associated with tumorigenesis and other diseases. In most animal cell types, the dynein motor complex is anchored at the cell cortex and exerts pulling forces on astral micro...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Vodicska, Barbara, Cerikan, Berati, Schiebel, Elmar, Hoffmann, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910412/
https://ncbi.nlm.nih.gov/pubmed/29679050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24682-8
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