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Dual Role of Cdc42 in Spindle Orientation Control of Adherent Cells

The spindle orientation is regulated by the interaction of astral microtubules with the cell cortex. We have previously shown that spindles in nonpolarized adherent cells are oriented parallel to the substratum by an actin cytoskeleton- and phosphatidylinositol 3,4,5-triphosphate [PtdIns(3,4,5)P3]-d...

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Detalhes bibliográficos
Main Authors: Mitsushima, Masaru, Toyoshima, Fumiko, Nishida, Eisuke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682030/
https://ncbi.nlm.nih.gov/pubmed/19273597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01713-08
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