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Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner
The orientation of mitotic spindles is tightly regulated in polarized cells, but it has been unclear whether there is a mechanism regulating spindle orientation in nonpolarized cells. Here we show that integrin-dependent cell adhesion to the substrate orients the mitotic spindle of nonpolarized cult...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1829369/ https://ncbi.nlm.nih.gov/pubmed/17318179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601599 |
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