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Switch of mitochondrial superoxide dismutase into a prooxidant peroxidase in manganese-deficient cells and mice
Superoxide radical anion (O(2)(•−)) and other Reactive Oxygen Species (ROS) are constantly produced during respiration. In mitochondria, the dismutation of O(2)(•−) is accelerated by the mitochondrial superoxide dismutase 2 (SOD2), an enzyme that has been traditionally associated with antioxidant pr...
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| Udgivet i: | Cell Chem Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5910218/ https://ncbi.nlm.nih.gov/pubmed/29398562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.01.007 |
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