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Withaferin-A Reduces Acetaminophen-Induced Liver Injury in Mice

Withaferin-A (WA) has anti-oxidant activities however, its therapeutic potential in acetaminophen (APAP) hepatotoxicity is unknown. We performed a proof-of-concept study to assess the therapeutic potential of WA in a mouse model that mimics APAP-induced liver injury (AILI) in humans. Overnight faste...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Jadeja, Ravirajsinh N., Urrunaga, Nathalie H., Dash, Suchismita, Khurana, Sandeep, Saxena, Neeraj Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909697/
https://ncbi.nlm.nih.gov/pubmed/26212553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.07.024
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