M1 Muscarinic Receptors Modify Oxidative Stress Response to Acetaminophen-Induced Acute Liver Injury

The role of muscarinic receptor subtypes in modulating acute liver injury is unknown. We detected M1 muscarinic receptors (M1R) expression in human and murine hepatocytes, and investigated the consequences of M1R deficiency on acute liver injury in vivo and inhibiting M1R activation on hepatocyte in...

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Publicado en:Free Radic Biol Med
Main Authors: Urrunaga, Nathalie H., Jadeja, Ravirajsinh N., Rachakonda, Vikrant, Ahmad, Daniel, McLean, Leon P., Cheng, Kunrong, Shah, Vijay, Twaddell, William S., Raufman, Jean-Pierre, Khurana, Sandeep
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392405/
https://ncbi.nlm.nih.gov/pubmed/25452146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.09.032
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