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Diff-seq: A high throughput sequencing-based mismatch detection assay for DNA variant enrichment and discovery

Much of the within species genetic variation is in the form of single nucleotide polymorphisms (SNPs), typically detected by whole genome sequencing (WGS) or microarray-based technologies. However, WGS produces mostly uninformative reads that perfectly match the reference, while microarrays require...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Aggeli, Dimitra, Karas, Vlad O, Sinnott-Armstrong, Nicholas A, Varghese, Vici, Shafer, Robert W, Greenleaf, William J, Sherlock, Gavin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909455/
https://ncbi.nlm.nih.gov/pubmed/29361139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky022
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