DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery

Here we report Digital RNA with pertUrbation of Genes (DRUG-seq), a high-throughput platform for drug discovery. Pharmaceutical discovery relies on high-throughput screening, yet current platforms have limited readouts. RNA-seq is a powerful tool to investigate drug effects using transcriptome chang...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Ye, Chaoyang, Ho, Daniel J., Neri, Marilisa, Yang, Chian, Kulkarni, Tripti, Randhawa, Ranjit, Henault, Martin, Mostacci, Nadezda, Farmer, Pierre, Renner, Steffen, Ihry, Robert, Mansur, Leandra, Keller, Caroline Gubser, McAllister, Gregory, Hild, Marc, Jenkins, Jeremy, Kaykas, Ajamete
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192987/
https://ncbi.nlm.nih.gov/pubmed/30333485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06500-x
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