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DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery

Here we report Digital RNA with pertUrbation of Genes (DRUG-seq), a high-throughput platform for drug discovery. Pharmaceutical discovery relies on high-throughput screening, yet current platforms have limited readouts. RNA-seq is a powerful tool to investigate drug effects using transcriptome chang...

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書目詳細資料
發表在:Nat Commun
Main Authors: Ye, Chaoyang, Ho, Daniel J., Neri, Marilisa, Yang, Chian, Kulkarni, Tripti, Randhawa, Ranjit, Henault, Martin, Mostacci, Nadezda, Farmer, Pierre, Renner, Steffen, Ihry, Robert, Mansur, Leandra, Keller, Caroline Gubser, McAllister, Gregory, Hild, Marc, Jenkins, Jeremy, Kaykas, Ajamete
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192987/
https://ncbi.nlm.nih.gov/pubmed/30333485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06500-x
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