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Sam68 offers selectively aimed modulation of transcription in cancer stem cells

In this issue of Cell Chemical Biology, Benoit et al. (2017) report the selective targeting of cancer stem cells (CSCs) by the ICG-001/CWP family of molecules. Their findings reveal that Sam68 is a novel transcriptional modulator uniquely required for the dysregulated Wnt/β-catenin signaling in CSCs...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Fu, Kai, Wan, Fengyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909376/
https://ncbi.nlm.nih.gov/pubmed/28732196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.07.003
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