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Sam68 offers selectively aimed modulation of transcription in cancer stem cells

In this issue of Cell Chemical Biology, Benoit et al. (2017) report the selective targeting of cancer stem cells (CSCs) by the ICG-001/CWP family of molecules. Their findings reveal that Sam68 is a novel transcriptional modulator uniquely required for the dysregulated Wnt/β-catenin signaling in CSCs...

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Dettagli Bibliografici
Pubblicato in:Cell Chem Biol
Autori principali: Fu, Kai, Wan, Fengyi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909376/
https://ncbi.nlm.nih.gov/pubmed/28732196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.07.003
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