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Bridged [2.2.1] bicyclic phosphine oxide facilitates catalytic γ-umpolung addition–Wittig olefination

A novel bridged [2.2.1] bicyclic phosphine oxide, devised to circumvent the waste generation and burdens of purification that are typical of reactions driven by the generation of phosphine oxides, has been prepared in three steps from commercially available cyclopent-3-ene-1-carboxylic acid. The per...

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Publicado en:Chem Sci
Main Authors: Zhang, Kui, Cai, Lingchao, Yang, Zhongyue, Houk, K. N., Kwon, Ohyun
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909331/
https://ncbi.nlm.nih.gov/pubmed/29732112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04381c
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