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Phosphine-catalyzed intramolecular γ-umpolung addition of α-aminoalkylallenic esters: facile synthesis of 3-carbethoxy-2-alkyl-3-pyrrolines

An array of N-tosylated α-aminoalkylallenic esters was prepared and their cyclization under the influence of nucleophilic phosphine catalysts was explored. The α-aminoalkylallenic esters were prepared through aza-Baylis–Hillman reactions or novel DABCO-mediated decarboxylative rearrangements of alle...

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Autors principals: Andrews, Ian P., Blank, Brian R., Kwon, Ohyun
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128507/
https://ncbi.nlm.nih.gov/pubmed/22526463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc31347b
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