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MUC1-C ACTIVATES POLYCOMB REPRESSIVE COMPLEXES AND DOWNREGULATES TUMOR SUPPRESSOR GENES IN HUMAN CANCER CELLS
The PRC2 and PRC1 complexes are aberrantly expressed in human cancers that have been linked with decreases in patient survival. MUC1-C is an oncoprotein that is overexpressed in diverse human cancers and is associated with a poor prognosis. Recent studies have supported a previously unreported funct...
Gorde:
| Argitaratua izan da: | Oncogene |
|---|---|
| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5908737/ https://ncbi.nlm.nih.gov/pubmed/29379165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0096-9 |
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