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MUC1-C REPRESSES THE RASSF1A TUMOR SUPPRESSOR IN HUMAN CARCINOMA CELLS

RASSF1A encodes a tumor suppressor that inhibits the RAS→RAF→MEK→ERK pathway and is one of the most frequently inactivated genes in human cancers. MUC1-C is an oncogenic effector of the cancer cell epigenome that is overexpressed in diverse carcinomas. We show here that MUC1-C represses RASSF1A expr...

詳細記述

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書誌詳細
出版年:Oncogene
主要な著者: Rajabi, Hasan, Hata, Tsuyoshi, Li, Wei, Long, Mark D, Hu, Qiang, Liu, Song, Raina, Deepak, Kui, Ling, Hong, Deli, Samur, Mehmet, Kufe, Donald
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872931/
https://ncbi.nlm.nih.gov/pubmed/31435022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0940-1
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