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Testosterone metabolites inhibit proliferation of castration- and therapy-resistant prostate cancer

Novel treatments for castration-resistant prostate cancer (CRPC) such as abiraterone acetate (AA) or enzalutamide effectively target the androgen pathway to arrest aberrant signalling and cell proliferation. Testosterone is able to inhibit tumour cell growth in CRPC. Estrogen receptor-beta (ERβ) bin...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bremmer, Felix, Jarry, Hubertus, Unterkircher, Valerie, Kaulfuss, Silke, Burfeind, Peter, Radzun, Heinz-Joachim, Ströbel, Philipp, Thelen, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908297/
https://ncbi.nlm.nih.gov/pubmed/29682196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24763
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