Testosterone metabolites inhibit proliferation of castration- and therapy-resistant prostate cancer

Novel treatments for castration-resistant prostate cancer (CRPC) such as abiraterone acetate (AA) or enzalutamide effectively target the androgen pathway to arrest aberrant signalling and cell proliferation. Testosterone is able to inhibit tumour cell growth in CRPC. Estrogen receptor-beta (ERβ) bin...

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Vydáno v:Oncotarget
Hlavní autoři: Bremmer, Felix, Jarry, Hubertus, Unterkircher, Valerie, Kaulfuss, Silke, Burfeind, Peter, Radzun, Heinz-Joachim, Ströbel, Philipp, Thelen, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908297/
https://ncbi.nlm.nih.gov/pubmed/29682196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24763
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