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Increased expression of CYP17A1 indicates an effective targeting of the androgen receptor axis in castration resistant prostate cancer (CRPC)

Recent breakthrough therapies targeting androgen receptor signalling in castration resistant prostate cancer (CRPC) involve multifunctional androgen receptor (AR) blockade and exhaustive androgen deprivation. Nevertheless, limitations to an enduring effectiveness of new drugs are anticipated in resi...

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Sonraí Bibleagrafaíochta
Main Authors: Bremmer, Felix, Jarry, Hubertus, Strauß, Arne, Behnes, Carl Ludwig, Trojan, Lutz, Thelen, Paul
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer International Publishing 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193971/
https://ncbi.nlm.nih.gov/pubmed/25332874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-574
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