Increased expression of CYP17A1 indicates an effective targeting of the androgen receptor axis in castration resistant prostate cancer (CRPC)

Recent breakthrough therapies targeting androgen receptor signalling in castration resistant prostate cancer (CRPC) involve multifunctional androgen receptor (AR) blockade and exhaustive androgen deprivation. Nevertheless, limitations to an enduring effectiveness of new drugs are anticipated in resi...

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Dettagli Bibliografici
Autori principali: Bremmer, Felix, Jarry, Hubertus, Strauß, Arne, Behnes, Carl Ludwig, Trojan, Lutz, Thelen, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193971/
https://ncbi.nlm.nih.gov/pubmed/25332874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-574
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