Increased expression of CYP17A1 indicates an effective targeting of the androgen receptor axis in castration resistant prostate cancer (CRPC)

Recent breakthrough therapies targeting androgen receptor signalling in castration resistant prostate cancer (CRPC) involve multifunctional androgen receptor (AR) blockade and exhaustive androgen deprivation. Nevertheless, limitations to an enduring effectiveness of new drugs are anticipated in resi...

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Detalhes bibliográficos
Main Authors: Bremmer, Felix, Jarry, Hubertus, Strauß, Arne, Behnes, Carl Ludwig, Trojan, Lutz, Thelen, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193971/
https://ncbi.nlm.nih.gov/pubmed/25332874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-574
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