Prospects of estrogen receptor β activation in the treatment of castration-resistant prostate cancer

Advanced prostate cancer can develop into castration-resistant prostate cancer (CRPC). This process is mediated either by intratumoral ligand synthesis or by mutations or aberrations of the androgen receptor (AR) or its cofactors. To date, no curative therapy for CRPC is available, as AR-targeted th...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Gehrig, Julia, Kaulfuß, Silke, Jarry, Hubertus, Bremmer, Felix, Stettner, Mark, Burfeind, Peter, Thelen, Paul
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471027/
https://ncbi.nlm.nih.gov/pubmed/28380417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16496
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