Increased expression of CYP17A1 indicates an effective targeting of the androgen receptor axis in castration resistant prostate cancer (CRPC)

Recent breakthrough therapies targeting androgen receptor signalling in castration resistant prostate cancer (CRPC) involve multifunctional androgen receptor (AR) blockade and exhaustive androgen deprivation. Nevertheless, limitations to an enduring effectiveness of new drugs are anticipated in resi...

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Bibliographic Details
Main Authors: Bremmer, Felix, Jarry, Hubertus, Strauß, Arne, Behnes, Carl Ludwig, Trojan, Lutz, Thelen, Paul
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193971/
https://ncbi.nlm.nih.gov/pubmed/25332874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-574
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