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Combination Therapy with Low-Dose IVIG and a C1-esterase Inhibitor Ameliorates Brain Damage and Functional Deficits in Experimental Ischemic Stroke

Acute ischemic stroke causes a high rate of deaths and permanent neurological deficits in survivors. Current interventional treatment, in the form of enzymatic thrombolysis, benefits only a small percentage of patients. Brain ischemia triggers mobilization of innate immunity, specifically the comple...

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Bibliografiske detaljer
Udgivet i:Neuromolecular Med
Main Authors: Chen, Xinzhi, Arumugam, Thiruma V., Cheng, Yi-Lin, Lee, Jong-Hwan, Chigurupati, Srinivasulu, Mattson, Mark P., Basta, Milan
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908217/
https://ncbi.nlm.nih.gov/pubmed/29299869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-017-8474-6
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