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Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death

Stroke is among the three leading causes of death worldwide and the most frequent cause of permanent disability. Brain ischemia induces an inflammatory response involving activated complement fragments. Here we show that i.v. Ig (IVIG) treatment, which scavenges complement fragments, protects brain...

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Detaylı Bibliyografya
Asıl Yazarlar: Arumugam, Thiruma V., Tang, Sung-Chun, Lathia, Justin D., Cheng, Aiwu, Mughal, Mohamed R., Chigurupati, Srinivasulu, Magnus, Tim, Chan, Sic L., Jo, Dong-Gyu, Ouyang, Xin, Fairlie, David P., Granger, Daniel N., Vortmeyer, Alexander, Basta, Milan, Mattson, Mark P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955802/
https://ncbi.nlm.nih.gov/pubmed/17715065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700506104
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