Intravenous immunoglobulin (IVIg) dampens neuronal toll-like receptor-mediated responses in ischemia

BACKGROUND: Ischemic stroke causes a high rate of deaths and permanent neurological damage in survivors. Ischemic stroke triggers the release of damage-associated molecular patterns (DAMPs) such as high-mobility group box 1 (HMGB1), which activate toll-like receptors (TLRs) and receptor for advanced...

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Pubblicato in:J Neuroinflammation
Autori principali: Lok, Ker Zhing, Basta, Milan, Manzanero, Silvia, Arumugam, Thiruma V
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409750/
https://ncbi.nlm.nih.gov/pubmed/25886362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0294-8
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