Current Challenges and Opportunities in Treating Glioblastoma

Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both intra- and intertumor heterogeneity, lending to resistance and eventual tumor recurrence. Large-scale genomic and proteo...

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Bibliographic Details
Published in:Pharmacol Rev
Main Authors: Shergalis, Andrea, Bankhead, Armand, Luesakul, Urarika, Muangsin, Nongnuj, Neamati, Nouri
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2018
Subjects:
Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907910/
https://ncbi.nlm.nih.gov/pubmed/29669750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.117.014944
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