Pak1 mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression

Insulin can stimulate hepatic expression of carbohydrate-responsive element-binding protein (ChREBP). As recent studies revealed potential metabolic beneficial effects of ChREBP, we asked whether its expression can also be regulated by the dietary polyphenol curcumin. We also aimed to determine mech...

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Detalhes bibliográficos
Publicado no:J Mol Cell Biol
Main Authors: Zeng, Kejing, Tian, Lili, Sirek, Adam, Shao, Weijuan, Liu, Ling, Chiang, Yu-Ting, Chernoff, Jonathan, Ng, Dominic S, Weng, Jianping, Jin, Tianru
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907843/
https://ncbi.nlm.nih.gov/pubmed/28992163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjx031
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