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The Area between Exchange Curves as a Measure of Conformational Differences in Hydrogen-Deuterium Exchange Mass Spectrometry Studies

Hydrogen-deuterium exchange mass spectrometry (HDX-MS) provides information about protein conformational mobility under native conditions. The area between exchange curves, A(bec), a functional data analysis concept, was adapted to the interpretation of HDX-MS data and provides a useful measure of e...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Mazur, Sharlyn J., Weber, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907500/
https://ncbi.nlm.nih.gov/pubmed/28236290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1615-1
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