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N-3 Polyunsaturated Fatty Acids Stimulate Bile Acid Detoxification in Human Cell Models

Cholestasis is characterized by the accumulation of toxic bile acids (BAs) in liver cells. The present study aimed to evaluate the effects of n-3 polyunsaturated fatty acids (n-3 PUFAs), such as docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids, on BA homeostasis and toxicity in human cell mode...

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Detalhes bibliográficos
Publicado no:Can J Gastroenterol Hepatol
Main Authors: Cieślak, Anna, Trottier, Jocelyn, Verreault, Mélanie, Milkiewicz, Piotr, Vohl, Marie-Claude, Barbier, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907406/
https://ncbi.nlm.nih.gov/pubmed/29850457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6031074
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