N-3 Polyunsaturated Fatty Acids Stimulate Bile Acid Detoxification in Human Cell Models

Cholestasis is characterized by the accumulation of toxic bile acids (BAs) in liver cells. The present study aimed to evaluate the effects of n-3 polyunsaturated fatty acids (n-3 PUFAs), such as docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids, on BA homeostasis and toxicity in human cell mode...

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Veröffentlicht in:Can J Gastroenterol Hepatol
Hauptverfasser: Cieślak, Anna, Trottier, Jocelyn, Verreault, Mélanie, Milkiewicz, Piotr, Vohl, Marie-Claude, Barbier, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907406/
https://ncbi.nlm.nih.gov/pubmed/29850457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6031074
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