Endoplasmic reticulum stress in perivascular adipose tissue promotes destabilization of atherosclerotic plaque by regulating GM-CSF paracrine

BACKGROUND: Perivascular adipose tissue (PVAT) accelerates plaque progression and increases cardiovascular risk. We tested the hypothesis that PVAT contributed to plaque vulnerability and investigated whether endoplasmic reticulum stress (ER stress) in PVAT played an important role in vulnerable pla...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Ying, Ru, Li, Sheng-Wei, Chen, Jia-Yuan, Zhang, Hai-Feng, Yang, Ying, Gu, Zhen-Jie, Chen, Yang-Xin, Wang, Jing-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907173/
https://ncbi.nlm.nih.gov/pubmed/29669585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1481-z
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