Nitric oxide selectively depletes macrophages in atherosclerotic plaques via induction of endoplasmic reticulum stress

BACKGROUND AND PURPOSE: Macrophages in atherosclerotic plaques have a tremendous impact on atherogenesis and plaque destabilization. We previously demonstrated that treatment of plaques in cholesterol-fed rabbits with the nitric oxide (NO) donor molsidomine preferentially eliminates macrophages, the...

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Hlavní autoři: Martinet, W, Croons, V, Timmermans, J-P, Herman, A G, De Meyer, G R Y
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2050816/
https://ncbi.nlm.nih.gov/pubmed/17700714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707426
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