Inhibition of inositol monophosphatase by lithium chloride induces selective macrophage apoptosis in atherosclerotic plaques

BACKGROUND AND PURPOSE: Lithium chloride (LiCl) inhibits inositol monophosphatase (IMPase) at therapeutic concentrations. Given that LiCl induces death in cultured macrophages and that macrophages play an active role in atherosclerotic plaque destabilization, we investigated whether LiCl would induc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: De Meyer, Inge, Martinet, Wim, Van Hove, Cor E, Schrijvers, Dorien M, Hoymans, Vicky Y, Van Vaeck, Luc, Fransen, Paul, Bult, Hidde, De Meyer, Guido RY
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2011
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058172/
https://ncbi.nlm.nih.gov/pubmed/21138421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01152.x
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