Inhibition of inositol monophosphatase by lithium chloride induces selective macrophage apoptosis in atherosclerotic plaques

BACKGROUND AND PURPOSE: Lithium chloride (LiCl) inhibits inositol monophosphatase (IMPase) at therapeutic concentrations. Given that LiCl induces death in cultured macrophages and that macrophages play an active role in atherosclerotic plaque destabilization, we investigated whether LiCl would induc...

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Hlavní autoři: De Meyer, Inge, Martinet, Wim, Van Hove, Cor E, Schrijvers, Dorien M, Hoymans, Vicky Y, Van Vaeck, Luc, Fransen, Paul, Bult, Hidde, De Meyer, Guido RY
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2011
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058172/
https://ncbi.nlm.nih.gov/pubmed/21138421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01152.x
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